Revolutionary Microchips Travel Inside Bloodstream to Target Brain Inflammation

Imagine tiny electronic devices that can reach specific brain areas without invasive surgery. Researchers led by MIT’s Deblina Sarkar have developed microscopic chips integrated with living cells, enabling targeted brain interventions through the bloodstream. These biohybrid devices can be injected via a standard syringe and migrate naturally to their destination, promising a less invasive alternative to traditional brain implants.

Initially dismissed by reviewers — with 35 rejections over two years — Sarkar’s team persisted against skepticism that such technology was science fiction. Their breakthrough came after six years of dedicated research, culminating in successful demonstrations of cell-assisted nanotechnology capable of reaching deep brain regions.

In 2022, after obtaining promising results, the team submitted their project for the NIH Director’s New Innovator Award. Remarkably, it was accepted on the first try, earning the highest impact score ever. Experts highlight that this approach could revolutionize medical treatments, making brain implants safer and more accessible.

As Dr. Sarkar explains, this innovation could pave the way for precise, minimally invasive therapies for neurological conditions, reducing risks associated with traditional surgery. This research exemplifies how perseverance in science can turn seemingly impossible ideas into reality, opening new frontiers in medical technology.

David Nield
David Nield

Dave is a freelance tech journalist with over 20 years covering gadgets, apps, and the web. From Stockport, England, he covers news, features, and reviews for TechRadar, focusing on phones, tablets, and wearables. He ensures top weekend breaking news and has bylines at Gizmodo, T3, PopSci, and others. He edited PC Explorer and The Hardware Handbook for years. Read me on x.com or linkedin.